
Women over 60 have a small increased risk of developing heart disease or stroke on combined oral (tablet) HRT. Studies suggest that medroxyprogesterone acetate and norethisterone have higher risks than dydrogesterone and progesterone. The risk with combined oestrogen and progestogen is greater than with oestrogen alone, or with newer HRT agents such as tibolone (sold as Livial or Xyvion), and may also depend on the type of progestogen used. There is no evidence to suggest that a woman with a family history of breast cancer will have an added increased risk of developing breast cancer if she uses HRT.

Women on oestrogen alone have no increased risk up to 15 years of usage. Women who use combined HRT for more than five years have a slightly increased risk. Women over 50 years of age who use combined oestrogen and progestogen (progesterone) replacement for less than five years have little or no increased risk of breast cancer.
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Talk to your doctor about any concerns you may have. These small risks must be balanced against the benefits of HRT for the individual woman. While HRT/MHT reduces the risk of some debilitating diseases, it may increase the risk of others. These side effects will usually settle within the first few months of treatment and may include: Some women experience side effects during the early stages of treatment, depending on the type and dose of HRT. HRT needs to be prescribed for each woman individually. cardiovascular disease – HRT has been shown to reduce cardiovascular disease markers when used around the time of menopause.bowel cancer – HRT slightly reduces the risk of colorectal cancer (bowel cancer).osteoporosis – HRT prevents further bone density loss, preserving bone integrity and reducing the risk of fractures, but it is not usually recommended as the first choice of treatment for osteoporosis, except in younger postmenopausal women (under the age of 60).diabetes – taking HRT around the time of menopause reduces a woman’s risk of developing diabetes.
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HRT reduces the risk of various chronic conditions that can affect postmenopausal women, including: Other therapies, including vaginal oestrogen products, antidepressants or other medications, may be used depending on the symptoms and risk factors.
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HRT is used to treat menopausal symptoms. HRT, also known as hormone therapy (HT) or menopausal hormone therapy (MHT), is medication containing the hormones that a woman’s body stops producing after menopause. These symptoms and physical changes can be managed in various ways, including lifestyle changes such as healthier eating and increased exercise, and by hormone replacement therapy (HRT). Many women, although not all, experience uncomfortable symptoms before and after menopause, including hot flushes, night sweats, sleep disturbance and vaginal dryness. It is a natural event that marks the end of the reproductive years, just as the first menstrual period during puberty marks the start. It occurs because a woman stops ovulating (releasing a mature egg once monthly), and her ovaries no longer produce oestrogen (one of the female sex hormones). Menopause marks the end of menstruation in a woman’s life.
